What Is The Function Of The Spleen? Immunity And Blood Health

By homehealthup

June 3, 2025

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Fact or myth: is the spleen an “unnecessary” organ? Contrary to popular misconception, the spleen plays an important role in overall human health. Not only is it part of the immune system, but it is also involved in blood filtration and red blood cell management.

Understanding the function of the spleen helps us to appreciate its contribution to health. This article will explore the important roles of the spleen, from the immune system to blood cell recycling and related health problems.

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What Is The Function Of The Spleen? 

Anatomy of the Spleen

Location and Structure

Located in the upper left abdomen, just below the diaphragm, the spleen is a soft, pliable organ that is dark red in color. The spleen is usually shaped like a large bean, with its size varying depending on the body and health of each person. Adjacent to the stomach in front and close to the ribs in the back, the spleen works tirelessly among other vital organs.

Size and Shape

The spleen is on average about 12 cm long, 7 cm wide and weighs about 150-200g. However, this size can vary depending on genetic factors and health conditions. The internal structure of the spleen consists of two main parts: red meat and white meat. The red meat is responsible for filtering the blood, while the white meat is active in the immune system.

Relationships With Other Agencies

Bordering the pancreas and the left kidney, the spleen is closely related to the digestive and circulatory systems. Thanks to its rich blood vessels, the spleen ensures blood circulation and performs its special tasks. Although often overlooked, each action of the spleen contributes greatly to maintaining overall health.

Main Functions of the Spleen

Role in the Immune System

The spleen plays an important role in defending the body against infection. It acts as a command center for the immune system, where white blood cells such as lymphocytes are produced and stored. When there is a signal of infection, the spleen releases these cells in response.

Blood Filtration and Red Blood Cell Recycling

In addition to supporting the immune system, the spleen is also a natural filter for the blood. It checks and removes old or damaged red blood cells, preventing them from clogging up the circulatory system. The spleen also plays a role in recycling iron from old red blood cells, thereby promoting the production of new blood cells.

Hematology Regulation

The spleen helps regulate blood flow by storing blood and releasing it only when needed, such as in situations of sudden blood loss.

With these comprehensive functions, the spleen not only performs important tasks for overall health but also plays an irreplaceable role in maintaining the body's biological balance.

The Role of the Spleen in the Immune System

Defense Against Infection

The spleen plays a central role in supporting the immune system by detecting and helping to destroy bacteria and viruses. This function is important when the body is invaded by pathogens.

Storage and Release of White Blood Cells

The spleen is home to a large number of white blood cells, mainly lymphocytes, which play a fundamental role in destroying bacteria and fighting infections. When the body is threatened by bacteria or viruses, the spleen releases a large number of white blood cells to fight.

Creating Antibodies

Antibodies play an important role in recognizing and attacking pathogens. The spleen performs the function of providing and releasing antibodies to protect the body. When foreign pathogens appear, these antibodies will quickly respond to protect the body from potential risks.

Stimulate Immune Response

The spleen is also involved in activating and enhancing the immune response through interactions with other immune cells, helping the body respond more quickly to health threats.

Blood Filtration and Red Blood Cell Management

Blood Filtration Process

The spleen plays a vital role in filtering the blood, ensuring that circulating blood is free of impurities and unhealthy cells. Through its complex network of arteries and veins, the spleen identifies and removes old or damaged red blood cells, preventing potential harm.

Management of Old Red Blood Cells

As old red blood cells are broken down, the spleen performs an ingenious recycling process. It separates and conserves important elements like iron for reuse in the formation of new red blood cells. This not only keeps the body from becoming iron deficient, but also supports the overall biological process.

Protect and Reuse

By breaking down hemoglobin into smaller components, the spleen not only contributes to the management of internal body resources but also maintains the smooth functioning of the circulatory system. This management helps stabilize blood quality and supports other important physiological functions.

Contribution of the Spleen to Blood Storage

Quality of blood reserve

The spleen plays an important role in maintaining blood reserves, helping the body to be ready to deal with emergencies. It is a storehouse of red and white blood cells, ready to be released when needed.

Release blood in emergency situations

In situations such as trauma, sudden blood loss, or lack of oxygen, the spleen immediately releases excess blood into the circulatory system. This helps to quickly replace lost blood, maintain stable blood pressure, and provide oxygen to vital organs.

Adjust blood volume as needed

The spleen plays a role in regulating blood volume in the body through flexible storage and release. This mechanism not only keeps blood pressure stable but also optimizes the use of blood cells according to the physiological needs of each body state, from rest to high activity.

The presence of the spleen, with its function of storing and regulating blood, is key to maintaining homeostasis and protecting overall health.

Common Disorders and Conditions Affecting the Spleen

Splenomegaly

Splenomegaly is a condition in which the spleen becomes larger than normal. It can be caused by infection, autoimmune disease, or blood system disorders. Symptoms include abdominal pain, fatigue, and easy bleeding.

Asplenia

Asplenia is a condition in which the spleen is absent, either congenitally or due to removal due to disease. Without a spleen, the body is susceptible to infection, especially from bacteria such as Streptococcus pneumoniae.

Trauma and Splenic Rupture

Physical trauma can lead to a ruptured spleen, causing internal bleeding. This condition requires prompt medical intervention to prevent severe blood loss.

Treatment and Prevention

Treatment depends on the underlying cause. For infections, antibiotics may be used. Surgery may be necessary if the spleen is very large or ruptured. Vaccinations and maintaining a healthy lifestyle can help protect the spleen and prevent potential complications.

Conclusion

The spleen plays a vital role in the immune system, from filtering blood, recycling red blood cells to storing blood. The health of the spleen not only directly affects the body's ability to protect against infection, but also ensures a balance in the recycling and storage of blood components.

The spleen, though often overlooked, has a major impact on overall health, emphasizing the importance of maintaining its health.

FAQs About the Spleen

Frequently Asked Questions (FAQs)

  • Can you live without a spleen? – Yes, it is possible for a person to live without a spleen, but the immune system will be impaired, making you more susceptible to infections.
  • What happens if the spleen is damaged? – When the spleen is damaged, it can lead to internal bleeding, infection, and requires emergency medical treatment.
  • How to keep the spleen healthy? – Maintaining a healthy lifestyle, eating a balanced diet, exercising regularly, and controlling infections can help protect the spleen.
  • Are there any specific symptoms that indicate a spleen problem? – Pain or a feeling of fullness in the upper left part of the abdomen, fatigue, and susceptibility to infections can be signs of a spleen problem.
  • How is an enlarged spleen diagnosed? – Diagnosis of an enlarged spleen is usually made through clinical examination and imaging tests such as ultrasound or CT scan.

About the author

Homehealthup is an avid researcher with a deep love of health. She specializes in writing research and reviews on new and essential topics in fitness and nutrition by thoroughly analyzing products based on user reviews, personal experiences, and feedback from forums.

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